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Page 1
An autocrine signaling circuit in hepatic stellate cells underlies advanced fibrosis in nonalcoholic steatohepatitis.
Wang S, Li K, Pickholz E, Dobie R, Matchett KP, Henderson NC, Carrico C, Driver I, Borch Jensen M, Chen L, Petitjean M, Bhattacharya D, Fiel MI, Liu X, Kisseleva T, Alon U, Adler M, Medzhitov R, Friedman SL. Wang S, et al. Among authors: matchett kp. Sci Transl Med. 2023 Jan 4;15(677):eadd3949. doi: 10.1126/scitranslmed.add3949. Epub 2023 Jan 4. Sci Transl Med. 2023. PMID: 36599008 Free PMC article.
Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis.
Dobie R, Wilson-Kanamori JR, Henderson BEP, Smith JR, Matchett KP, Portman JR, Wallenborg K, Picelli S, Zagorska A, Pendem SV, Hudson TE, Wu MM, Budas GR, Breckenridge DG, Harrison EM, Mole DJ, Wigmore SJ, Ramachandran P, Ponting CP, Teichmann SA, Marioni JC, Henderson NC. Dobie R, et al. Among authors: matchett kp. Cell Rep. 2019 Nov 12;29(7):1832-1847.e8. doi: 10.1016/j.celrep.2019.10.024. Cell Rep. 2019. PMID: 31722201 Free PMC article.
Indian Hedgehog release from TNF-activated renal epithelia drives local and remote organ fibrosis.
O'Sullivan ED, Mylonas KJ, Xin C, Baird DP, Carvalho C, Docherty MH, Campbell R, Matchett KP, Waddell SH, Walker AD, Gallagher KM, Jia S, Leung S, Laird A, Wilflingseder J, Willi M, Reck M, Finnie S, Pisco A, Gordon-Keylock S, Medvinsky A, Boulter L, Henderson NC, Kirschner K, Chandra T, Conway BR, Hughes J, Denby L, Bonventre JV, Ferenbach DA. O'Sullivan ED, et al. Among authors: matchett kp. Sci Transl Med. 2023 May 31;15(698):eabn0736. doi: 10.1126/scitranslmed.abn0736. Epub 2023 May 31. Sci Transl Med. 2023. PMID: 37256934
Cancer Burden Is Controlled by Mural Cell-β3-Integrin Regulated Crosstalk with Tumor Cells.
Wong PP, Muñoz-Félix JM, Hijazi M, Kim H, Robinson SD, De Luxán-Delgado B, Rodríguez-Hernández I, Maiques O, Meng YM, Meng Q, Bodrug N, Dukinfield MS, Reynolds LE, Elia G, Clear A, Harwood C, Wang Y, Campbell JJ, Singh R, Zhang P, Schall TJ, Matchett KP, Henderson NC, Szlosarek PW, Dreger SA, Smith S, Jones JL, Gribben JG, Cutillas PR, Meier P, Sanz-Moreno V, Hodivala-Dilke KM. Wong PP, et al. Among authors: matchett kp. Cell. 2020 Jun 11;181(6):1346-1363.e21. doi: 10.1016/j.cell.2020.02.003. Epub 2020 May 29. Cell. 2020. PMID: 32473126 Free article.
Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth.
Lechertier T, Reynolds LE, Kim H, Pedrosa AR, Gómez-Escudero J, Muñoz-Félix JM, Batista S, Dukinfield M, Demircioglu F, Wong PP, Matchett KP, Henderson NC, D'Amico G, Parsons M, Harwood C, Meier P, Hodivala-Dilke KM. Lechertier T, et al. Among authors: matchett kp. Nat Commun. 2020 Jun 4;11(1):2810. doi: 10.1038/s41467-020-16618-6. Nat Commun. 2020. PMID: 32499572 Free PMC article.
Spatial genomics: mapping human steatotic liver disease.
Matchett KP, Paris J, Teichmann SA, Henderson NC. Matchett KP, et al. Nat Rev Gastroenterol Hepatol. 2024 Apr 23. doi: 10.1038/s41575-024-00915-2. Online ahead of print. Nat Rev Gastroenterol Hepatol. 2024. PMID: 38654090 Review.
Author Correction: Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth.
Lechertier T, Reynolds LE, Kim H, Pedrosa AR, Gómez-Escudero J, Muñoz-Félix JM, Batista S, Dukinfield M, Demircioglu F, Wong PP, Matchett KP, Henderson NC, D'Amico G, Parsons M, Harwood C, Meier P, Hodivala-Dilke KM. Lechertier T, et al. Among authors: matchett kp. Nat Commun. 2023 Sep 6;14(1):5446. doi: 10.1038/s41467-023-41239-0. Nat Commun. 2023. PMID: 37673931 Free PMC article. No abstract available.
Loss of Integrin αvβ8 in Murine Hepatocytes Accelerates Liver Regeneration.
Greenhalgh SN, Matchett KP, Taylor RS, Huang K, Li JT, Saeteurn K, Donnelly MC, Simpson EEM, Pollack JL, Atakilit A, Simpson KJ, Maher JJ, Iredale JP, Sheppard D, Henderson NC. Greenhalgh SN, et al. Among authors: matchett kp. Am J Pathol. 2019 Feb;189(2):258-271. doi: 10.1016/j.ajpath.2018.10.007. Epub 2018 Nov 16. Am J Pathol. 2019. PMID: 30448409 Free PMC article.
Transfer of hepatocellular microRNA regulates cytochrome P450 2E1 in renal tubular cells.
Matthews O, Morrison EE, Tranter JD, Starkey Lewis P, Toor IS, Srivastava A, Sargeant R, Rollison H, Matchett KP, Kendall TJ, Gray GA, Goldring C, Park K, Denby L, Dhaun N, Bailey MA, Henderson NC, Williams D, Dear JW. Matthews O, et al. Among authors: matchett kp. EBioMedicine. 2020 Dec;62:103092. doi: 10.1016/j.ebiom.2020.103092. Epub 2020 Nov 21. EBioMedicine. 2020. PMID: 33232872 Free PMC article.